How do seratonin reputake inhibitors and prohibitors work?

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lax<3
User offline. Last seen 1 year 47 weeks ago. Offline
Joined: 03/13/2010

Im doing research on some medications (specifically meridia or sibutramine vs prozac or other anti-depressants) And I'm having a hard time understanding the scientific wording for these medications and how they work, and why it's bad to mix them.

One is an inhibitor and one is a prohibitor for seratonin reputake? I think? Whether someone could explain this in plain english for me I would really appreciate it.

Also, for someone who is depressed, whould taking something like meridia/sibutramine make you more depressed?


Clint C
User offline. Last seen 1 year 47 weeks ago. Offline
Joined: 03/13/2010

mm idk

Ms. Pussy Lips
User offline. Last seen 1 year 47 weeks ago. Offline
Joined: 03/13/2010

I do know that serotonin is a very important neurotransmitter and that your brain won't function properly if you have low serotonin levels. Anything that inhibits serotonin could cause serious mental disorder. I myself used the ancient chinese method of raising my serotonin by using the Temporal Tap technique.

John
User offline. Last seen 2 years 9 weeks ago. Offline
Joined: 12/04/2009

No, the problem is that you could develop serotonin syndrome or a neuroleptic malignant disorder if it is really bad. That condition involves being overheated, psychotic, and at risk of seizures (which could cause brain damage or kill you). This is a major and important drug interaction.

Meridia is sort of a light stimulant, helps you burn calories also stimulates your synapses to release serotonin. Ssri's are more inhibiting reuptake of serotonin into the releasing neuron, so you have more serotonin in the synapses. So whether you make serotonin go into the synapse with one drug, and stop the serotonin from going back into the original synapse with another drug - what do you get? Too much serotonin.

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